将白血病细胞培养成集落,用这种集落进行药物敏感性试验,选择有效的药剂,可望成为治疗白血病的有效方法。新?大学森山美昭氏报告了急性白血病细胞集落的药物敏感性及药物临床疗效的分析结果。据报告,各病例对药剂敏感性明显不同,用敏感性高的药剂时,所有患者均缓解,而敏感性低时,效果就不好。因此,根据各病例选择使用敏感性高的药剂,就有可能得到较高的治疗效果。白血病不是因白细胞的分化,而是由于造血干细胞的异常增殖引起的。急性白血病也是来自成熟前期细胞(L—CFU)的,因此,应用以L—CFU为标的药剂可取得良好效果。为了研究L—CFU的药物敏感性,而使用集落。森山氏应用他研究成功的“二步法”制成了集落。方法是,首先将急性白血病细胞放在液体中,用 Leukemia cells cultured into colonies, using this colony for drug susceptibility testing, the choice of effective agents, is expected to be an effective method of treatment of leukemia. Shin-ichi University Moriyama Shizuka reported the drug sensitivity of acute leukemia cell colonies and analysis of the clinical efficacy of the drug. It was reported that the sensitivity of each case significantly different agents, with highly sensitive agents, all patients were relieved, and the sensitivity is low, the effect is not good. Therefore, depending on the case choose to use highly sensitive agents, it is possible to get a higher therapeutic effect. Leukemia is not caused by leukocyte differentiation, but rather by abnormal proliferation of hematopoietic stem cells. Acute leukemia is also from pre-mature cells (L-CFU), therefore, the application of L-CFU-based drugs can achieve good results. In order to study the drug sensitivity of L-CFU, colonies were used. Mori Yamauchi made the colony using his “two-step method” of successful research. The method is, first of all the acute leukemia cells in liquid, with