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目的:了解住院肿瘤患者细菌感染的菌群分布状况及耐药趋势。方法:分析1997年～1998年住院恶性肿瘤患者送检标本中的细菌种类和药敏情况。结果:从临床送检的2142份标本中共检出693株细菌,居前四位的优势菌依次为假单胞菌29.58%,肠杆菌属细菌27.99%,葡萄球菌20.92%,真菌20.34%。本组细菌对青霉素、氨苄青霉素和磺胺大多耐药。阴性杆菌对新一代广谱抗生素和头孢菌素类耐药率一般均超过50%;阳性球菌除对氧氟沙星敏感外,对其它抗生素耐药率均较高。结论:对肿瘤患者必须严格控制抗生素的滥用,否则可能造成严重的后果,应当引起临床医师的高度重视。
Objective: To understand the distribution of bacteria in hospitalized patients with bacterial infection and drug resistance trends. Methods: To analyze the bacterial species and drug sensitivity in the specimens from 1997 to 1998 in hospitalized patients with malignant tumors. Results: A total of 693 strains of bacteria were detected from 2142 specimens clinically tested. The top four dominant bacteria were Pseudomonas sp. 29.58%, Enterobacter sp. 27.99%, Staphylococcus sp 20.92% and fungi 20.34%. The group of bacteria on penicillin, ampicillin and sulfa mostly resistant. Negative bacilli for a new generation of broad-spectrum antibiotics and cephalosporins resistant rates are generally more than 50%; positive cocci in addition to ofloxacin sensitive, resistant to other antibiotics were higher. Conclusion: The cancer patients must strictly control the abuse of antibiotics, otherwise it may have serious consequences, which should arouse the clinician’s attention.