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目的:分析蒙脱石散保留灌肠和口服不同给药途径对小儿腹泻的疗效影响。方法:对2008年2月~2011年5月间使用蒙脱石散治疗的腹泻患儿资料63例进行回顾性分析。结果:治疗一个疗程后,治疗组总有效率93.6%;对照组总有效率80.6%,两组总有效率之间有统计学差异(P<0.05)。两组患儿总住院时间有显著统计学差异(P<0.01)。两组治疗后大便次数均较治疗前减少,且治疗组改善情况优于对照组,差异均有统计学意义(P<0.01)。结论:临床上治疗小儿腹泻不必拘泥于传统的口服给药途径,保留灌肠也不失为一种较好的方法。
OBJECTIVE: To analyze the effect of montmorillonite retention enema and oral administration on the curative effect of pediatric diarrhea. Methods: The data of 63 children with diarrhea treated with montmorillonite powder between February 2008 and May 2011 were retrospectively analyzed. Results: After a course of treatment, the total effective rate was 93.6% in the treatment group and 80.6% in the control group. The total effective rate was significantly different between the two groups (P <0.05). There was a significant difference in total length of stay between the two groups (P <0.01). The number of stool in both groups after treatment decreased compared with before treatment, and the treatment group improved better than the control group, the difference was statistically significant (P <0.01). Conclusion: Clinical treatment of children with diarrhea need not rigidly adhere to the traditional oral route of administration, retention enema is a good way.