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为探讨妇科良、恶性肿瘤患者CD3AK细胞的体外增殖能力，对其外周血淋巴细胞用CD3MAb＋IL－2诱导CD3AK细胞，体外动态观察CD3AK细胞增殖倍数，并与同期培养的LAK细胞进行对比。结果：①良性肿瘤组CD3AK细胞在培养第1周，增殖倍数高于恶性肿瘤组，但无显著性差异（P＞0．05），第2、3、4周，良、恶性肿瘤组CD3AK的增殖倍数较接近；②LAK细胞增殖倍数，在良性肿瘤组培养第1周时显著高于恶性肿瘤组（P＜0．05），培养第2、3周也高于恶性肿瘤组，但无统计学意义（P＞0．05）。结果提示：CD3AK细胞和LAK细胞短期培养时，不宜取材于恶性肿瘤患者。
To investigate the proliferative ability of CD3AK cells in patients with benign and malignant gynecological diseases in vitro, CD3AK cells were induced by CD3MAb + IL-2 in peripheral blood lymphocytes. The proliferation of CD3AK cells was observed in vitro and compared with that of LAK cells cultured in the same period. Results: ① In the first week of culture, CD3AK cells of benign tumor group had higher proliferation rate than that of malignant tumor group, but no significant difference (P> 0.05) (2) The multiplication rate of LAK cells was significantly higher than that of malignant tumor group (P <0.05) at the first week of culture in benign tumor group, and also higher than that of malignant tumor group at the second and third week of culture Significance (P> 0.05). The results suggest that: CD3AK cells and LAK cells when cultured for short, should not be drawn from patients with malignant tumors.