Lyme病是由蜱咬所致的螺旋体感染性疾病,典型病例多发生在夏季,具有特征性的皮损——慢性游走性红斑(ECM),并可伴流感样或脑膜炎样症状,以后且可陆续发生神经系统病变、心脏异常、关节炎等。过去,诊断本病主要根据临床,特別强调ECM是本病唯一的临床标记。早期诊断十分重要,因及时的应用适当的抗生素可预防以后各种病变的发生。自1982年发现Lyme螺旋体后,病原体 Lyme disease is a spirochete infectious disease caused by tick bites. The typical cases occur in the summer with characteristic skin lesions - chronic migratory erythema (ECM) and may be associated with flu-like or meningitis-like symptoms And may have nervous system diseases, abnormal heart, arthritis and so on. In the past, the diagnosis of the disease mainly based on clinical, with special emphasis on ECM is the only clinical marker of the disease. Early diagnosis is very important, due to the timely application of appropriate antibiotics can prevent the occurrence of various diseases later. Since the discovery of Lyme spirochaetes in 1982, the pathogen