内皮素 (ＥＴ)是含 2 1个氨基酸残基的多肽 ,研究表明ＥＴ在低氧性肺动脉高压的发生和发展过程中起重要作用。米力农为新一代磷酸二酯酶抑制剂 ,具有增强心肌收缩力、舒张支气管和血管平滑肌的作用。曾有报道低氧性肺动脉高压患者应用米力农治疗后 ,平均肺动脉压和肺血管阻力明 Endothelin (ET) is a polypeptide containing 21 amino acid residues. Studies have shown that ET plays an important role in the pathogenesis and progression of hypoxic pulmonary hypertension. Milrinone as a new generation of phosphodiesterase inhibitors, with increased myocardial contractility, relaxation of bronchial and vascular smooth muscle role. It has been reported in patients with hypoxic pulmonary hypertension after milrinone treatment, the average pulmonary arterial pressure and pulmonary vascular resistance