肾源性纤维性皮肤病/肾源性系统性纤维化(NFD/NSF)是一种在严重的肾病下自发获得的出疹性皮肤损害性疾病,可伴发全身皮肤和结缔组织系统性纤维化。这是一个慢性进展性和致死性疾病。其病因尚未明确。最近有报道指出使用含钆造影剂和NFD/NSF的发病有较强的相关性。本文就NFD/NSF的流行病学,临床病史和体格检查,病理生理学和组织学的特征,含钆造影剂在NFD/NSF发病中所扮演的角色,以及放射科医师在这个问题上应该注意的事项做一综述。 Renal Dermatofibrosis / Renal Systemic Fibrosis (NFD / NSF) is an erosive skin lesion that occurs spontaneously under severe kidney disease and may be associated with systemic skin and connective tissue fibers The This is a chronic progressive and fatal disease. The etiology is not yet clear. Recently it has been reported that there is a strong correlation between the use of gadolinium-containing contrast agents and the incidence of NFD / NSF. In this paper, the epidemiology, clinical history and physical examination of NFD / NSF, the characteristics of pathophysiology and histology, the role of gadolinium-containing contrast medium in the pathogenesis of NFD / NSF, and what radiologists should pay attention to in this issue Things to do a review.