脑胶质瘤是颅内肿瘤最常见的恶性肿瘤,胶质瘤的侵袭性生长方式及周围组织的弥漫性浸润,手术难以完全切除,术后容易复发,这决定了胶质瘤患者的预后,中位生存期时间大约为1年。虽经手术及术后放疗,化疗等方法措施也不能明显改善预后差的现状。长期以来,脑胶质瘤的病因、起源和治疗一直是神经外科领域研究的热点问题,并存在多种 Glioma is the most common malignant tumor of intracranial tumors, glioma invasive growth and the surrounding tissue diffuse infiltration, surgery is difficult to completely remove the postoperative recurrence, which determines the prognosis of patients with glioma, The median survival time is about 1 year. Although surgery and postoperative radiotherapy, chemotherapy and other methods and measures can not significantly improve the status of poor prognosis. For a long time, the etiology, origin and treatment of glioma have been the hot issues in the field of neurosurgery, and there are many