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肝硬化患者肾素-血管紧张素-醛固酮系统(RAA)亢进,与腹水的发生关系密切;卡托普利(captopril,又名巯甲丙脯氨酸)为人工合成的血管紧张素转换酶抑制剂,具有抑制血管紧张素Ⅰ转换为血管紧张素Ⅱ的作用。国外学者尝试用於治疗肝硬化腹水患者,取得了良好的效果。本文观察了卡托普利对32例肝硬化腹水患者的治疗作用,并进行了27例对照研究。
Renal-angiotensin-aldosterone system (RAA) hyperactivity in cirrhotic patients is closely related to the occurrence of ascites; captopril (also known as captopril) is a synthetic angiotensin converting enzyme inhibitor Agent, has the effect of inhibiting the conversion of angiotensin I to angiotensin II. Foreign scholars try to treat patients with cirrhosis and ascites, and achieved good results. In this paper, the therapeutic effect of captopril on 32 patients with cirrhosis and ascites was observed and 27 control studies were performed.