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目的探讨布地奈德联合肾上腺素雾化吸入治疗急性喉炎患儿的临床疗效。方法选取2014年11月至2016年3月于辽宁省营口市老边区人民医院接受治疗的132例急性喉炎患儿为研究对象,随机分为A组、B组、C组,各44例。A组患儿采用地塞米松静脉滴注方案治疗,B组患儿采用单纯布地奈德雾化方案治疗,C组患儿采用布地奈德联合肾上腺素雾化方案治疗,比较3组患儿的治疗效果。结果 B组、C组患儿呼吸困难、声音嘶哑、吸气性喉鸣、犬吠样咳嗽消失时间均明显短于A组,且C组患儿吸气性喉鸣、犬吠样咳嗽消失时间均明显短于B组,差异均有统计学意义(均P<0.05);B组、C组患者治疗的总有效率均明显高于A组,差异均有统计学意义(均P<0.05)。结论布地奈德联合肾上腺素雾化吸入治疗治疗急性喉炎临床疗效显著,且安全性高。
Objective To investigate the clinical efficacy of budesonide combined with epinephrine nebulization in the treatment of children with acute laryngitis. Methods From November 2014 to March 2016, 132 children with acute laryngitis treated in Laobian District People’s Hospital of Yingkou City of Liaoning Province were selected as study objects and randomly divided into A group, B group and C group, with 44 cases in each group. A group of children treated with dexamethasone intravenous infusion, B group of children treated with simple budesonide atomization program, C group with budesonide and epinephrine nebulization scheme, the three groups of children treatment effect. Results In group B and group C, the dyspnea, hoarseness, inspiratory larynx and bark-like cough disappeared significantly in group B and group C, respectively, and the duration of inhalation larynx and bark-like cough disappeared in group B and group C (P <0.05). The total effective rate of treatment in group B and group C was significantly higher than that in group A, the differences were statistically significant (all P <0.05). Conclusion Budesonide combined with epinephrine nebulization for the treatment of acute laryngitis has obvious clinical efficacy and safety.