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兔灌胃茵栀黄3天,可加速注入的非结合胆红素自血浆排泄;苯巴比妥灌胃3天可产生类似的作用,但较弱。给大白鼠腹腔内注射茵栀黄或苯巴比妥3天,并结扎其胆总管,茵栀黄或苯巴比妥处理的动物其间接胆红素水平较对照组为低,而肝胆红素含量和血浆直接胆红素水平增高。提示菌栀黄和苯巴比妥具有相同的降低血清间接胆红素的作用。
The rabbits were treated with Yin Zhi Huang for 3 days, which accelerated the infusion of non-conjugated bilirubin excreted from the plasma; phenobarbital administered for 3 days could produce a similar effect but weaker. Intraperitoneal injection of Yinzhihuang or phenobarbital into rats was performed for 3 days, and the common bile duct was ligated. The ratio of indirect bilirubin in the animals treated with Yinzhihuang or Phenobarbital was lower than that in the control group. Content and plasma direct bilirubin levels increased. It is suggested that bacterioside yellow and phenobarbital have the same effect of reducing serum indirect bilirubin.