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多项研究表明,糖尿病患者因其代谢紊乱、组织抵抗力减弱等原因,导致肺结核(PTB)发生率显著高于非糖尿病患者,且因机体的局部免疫应答加重肺组织内局部病灶的局限化,使PTB迁延不愈,与此同时,PTB也可加重糖尿病病情。本研究采用1:1配对的对照研究,比较T2DM合并PTB患者与单独PTB患者的肺功能状态,分析T2DM合并PTB患者肺通气功能、弥散功能的影响因素。
A number of studies have shown that patients with diabetes due to their metabolic disorders, decreased tissue resistance and other reasons, leading to a significantly higher incidence of pulmonary tuberculosis (PTB) than non-diabetic patients, and the body’s local immune response aggravate local limitations of pulmonary lesions, PTB delayed healing, at the same time, PTB can also aggravate diabetes. In this study, a 1: 1 matched control study was conducted to compare the pulmonary function status between T2DM patients with PTB and PTB alone and to analyze the influencing factors of pulmonary ventilation and diffusion in patients with T2DM complicated with PTB.