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7肾功能损害时药物应用原则肾功能损害时应用药物的常规剂量,可因肾脏对这些药物的代谢和排泄障碍使其在血液和组织中蓄积达到中毒水平,促使肾功能进一步减损。这种药物的中毒表现可被患者原有疾病的症状所掩盖,不易引起医生重视。因此,肾功能不全者必须根据以下原则综合考虑。
7 principles of renal damage when the drug application of renal dysfunction, the application of conventional doses of drugs can be due to kidney metabolism and excretion of these drugs barriers to accumulation in the blood and tissues to achieve the level of poisoning, prompting further impairment of renal function. The poisoning of this drug can be covered by the symptoms of the patient’s original disease, not easy to arouse the doctor’s attention. Therefore, renal insufficiency must be based on the following principles.