陕西省农村人群高血压性视网膜病变的流行病学调查

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目的:调查陕西省农村≥50岁人群高血压性视网膜病的患病率及其相关影响因素。方法:2003-07/12,采用整体随机分层抽样法在陕西省洋县、靖边县及富平县调查8500人,其中≥50岁2125人中受检1775人,所有受检人员均进行标准问卷调查及详细的眼科检查,包括应用标准对数视力表(logMAR)视力表检查视力、裂隙灯显微镜检查晶状体、散瞳后直接检眼镜检查视网膜,若眼底表现有视网膜动静脉不规则狭窄、视网膜渗出(黄白色硬性渗出和棉绒斑状软性渗出)及出血、视盘水肿,则诊断为高血压性视网膜病变。受检者于坐位测量血压。结果:≥50岁人群中有1775人完成了相关检查,受检率为83.53%。高血压性视网膜病变的患病率为6.20%(95%CI,5.14,7.45)。通过Mantel-Haenszel分层分析,显示高血压性视网膜病变的患病率随年龄的增长而显著增加(P<0.01),虽然男性高血压性视网膜病变(6.56%)患病率高于女性(5.89%),但其差异无显著统计学意义(P=0.743)。高血压患者的高血压性视网膜病变患病率明显高于非高血压受检者。通过应用多因素logistic回归分析显示年龄、性别、文化程度、吸烟、饮酒、高血压和血压水平与高血压性视网膜病变的发生有密切联系。结论:陕西省农村≥50岁人群中高血压性视网膜病变较常见。在此人群中年龄、高血压病及血压水平是高血压性视网膜病变发生的重要危险因素。 Objective: To investigate the prevalence and related risk factors of hypertensive retinopathy in rural people aged> 50 years in Shaanxi Province. Methods: Totally 8500 people were surveyed in Yangxian County, Jingbian County and Fuping County in Shaanxi Province using the whole random stratified sampling method from July 2003 to December 12, of which 1,775 were from 2125 ≥50 years of age, Questionnaire investigation and detailed ophthalmological examination, including the use of standard logarithmic visual acuity chart (logMAR) vision chart visual acuity, slit lamp microscopic examination of the lens, direct ophthalmoscopy after dilation of the retina, if the fundus showed irregular retinal artery and vein narrow, the retina Exudation (yellow-white hard exudate and lint-like soft exudate) and bleeding, optic disc edema, the diagnosis of hypertensive retinopathy. Subjects measured blood pressure in the sitting position. Results: 1775 people over 50 years of age completed the relevant examination, the examination rate was 83.53%. The prevalence of hypertensive retinopathy was 6.20% (95% CI, 5.14, 7.45). Stratified analysis by Mantel-Haenszel showed that the prevalence of hypertensive retinopathy was significantly increased with age (P <0.01). Although the prevalence of hypertensive retinopathy in men (6.56%) was higher than that in women %), But the difference was not statistically significant (P = 0.743). The prevalence of hypertensive retinopathy in hypertensive patients is significantly higher than that in non-hypertensive subjects. Multivariate logistic regression analysis showed that age, gender, education level, smoking, drinking, hypertension and blood pressure were closely related to the occurrence of hypertensive retinopathy. Conclusion: Hypertensive retinopathy is more common in rural people aged ≥50 years in Shaanxi Province. In this population age, hypertension and blood pressure levels are important risk factors for the development of hypertensive retinopathy.
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