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目的总结佛山市顺德区先天性甲状腺功能减低症(CH)13年的筛查情况、了解本地区CH发病情况及治疗效果。方法新生儿出生72 h后取足跟血,制成干血滤纸片,测定干血片TSH浓度,对于促甲状腺激素(TSH)≥8 mU/L的可疑CH患儿,召回并进行确诊。结果顺德区自2001年开展新生儿疾病筛查10多年以来,筛查率逐年提高,从最初的81.67%提高到了去年的98.89%,10年来共确诊CH患儿150例,发病率为1/1993。结论顺德区CH发病率为1/1993,基本符合国内CH的发病率。CH患儿都能得到早期确诊,治疗效果满意。
Objective To summarize the 13-year screening of congenital hypothyroidism (CH) in Shunde District of Foshan City to understand the incidence of CH in this area and its therapeutic effect. Methods The hematopoietic stem cells were obtained 72 h after birth. Blood samples were collected to determine the concentration of TSH in dried blood samples. Patients with suspected CH with thyroid stimulating hormone (TSH) ≥8 mU / L were recalled and diagnosed. Results The screening rate of neonatal diseases in Shunde District increased from 81.67% to 98.89% of the previous year for more than 10 years since 2001. A total of 150 CH patients were diagnosed in 10 years, the incidence was 1/1993 . Conclusions The incidence of CH in Shunde District is 1/1993, basically in line with the incidence of CH in China. CH children can be diagnosed early, the treatment effect is satisfactory.