采用柯柯豆脂及硬脂酸丙二醇酯做基质,分别加入等量阿司匹林(0.3g 阿司匹林栓)制成两种栓剂,家兔直肠给药,于不同时间由心脏取血,在72型分光光度计上测光密度,在预先制成的水杨酸标准曲线图上查出血清中药物相对含量即血药浓度。用坐标纸绘出药-时曲线,结果两条曲线为平行线,两种基质达峰时 Corolla sojae and stearic acid propylene glycol ester were used as the matrix, and two kinds of suppositories were prepared by adding equal amount of aspirin (0.3g aspirin suppository). The rabbits were rectally administered with blood from the heart at different times. After 72 hours of spectrophotometry Calculate the metering density, the salicylic acid standard curve prepared in advance to detect the relative content of serum drug concentration. Draw the medicine - time curve with the coordinate paper, the result two curves are parallel lines, when two kinds of matrix reach the peak