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目的探讨羚角钩藤汤加减灌肠法在手足口病重症2期(神经系统受累期)中的临床疗效与机理。方法选取收治的100例手足口病2期患儿并随机分为治疗组与对照组。治疗组予常规西药加中药灌肠治疗,对照组予常规西药加生理盐水灌肠治疗,重点比较两组患儿临床疗效(有效率,发热、肢体抖动次数、平均住院日)。结果中药治疗组与对照组总有效率比较有统计学意义(P<0.05),显著有效率及无效率均有显著统计学意义(P<0.01);治疗组与对照组在发热好转及肢体抖动比较有显著统计学意义(P<0.01),平均住院日有统计学意义(P<0.05)。结论羚角钩藤汤加减灌肠治疗小儿手足口病2期有显著临床疗效,值得推广。
Objective To investigate the clinical effects and mechanism of gongtou gouteng decoction in the treatment of severe stage 2 HFMD (nervous system involvement stage). Methods Two hundred children with HFMD were selected and randomly divided into treatment group and control group. The treatment group was treated with conventional western medicine and traditional Chinese medicine enema. The control group was treated with conventional western medicine and saline enema. The clinical efficacy (effective rate, fever, limb jitter and average length of stay) of the two groups were compared. Results The total effective rate of the Chinese medicine treatment group and the control group was statistically significant (P <0.05), significant efficiency and inefficiency were statistically significant (P <0.01); the treatment group and the control group in the fever and limb jitter There was significant statistical significance (P <0.01), and the average length of stay was statistically significant (P <0.05). Conclusions Linggu gouteng decoction for the treatment of children with hand, foot and mouth disease stage 2 has a significant clinical effect, it is worth promoting.