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支气管肺发育不良(bronchopulmonary dysplasia,BPD)是早产儿最常见的并发症,同时也是新生儿重症监护病房最棘手的问题之一。近年随着呼吸管理水平的改进,以肺实质纤维化为特征的经典型BPD逐渐被以肺泡及肺微血管发育不良为特征的新型BPD取代。而宫内感染是新型BPD的重要原因之一,了解宫内感染与BPD的相互关联,并针对性采取早期干预措施,对减少BPD的发病率有重大意义。
Bronchopulmonary dysplasia (BPD) is the most common complication of preterm infants and one of the most problematic problems in neonatal intensive care units. In recent years, with the improvement of the level of respiratory management, classic BPD characterized by pulmonary parenchymal fibrosis is gradually replaced by a new type of BPD characterized by alveoli and pulmonary microvascular dysplasia. Intrauterine infection is one of the important reasons of new BPD. To understand the correlation between intrauterine infection and BPD and to take early interventions targeted to reduce the incidence of BPD is of great significance.