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作者用快速荧光灶抑制试验(RFFIT)检测了美国人及和平队志愿者(PCV)的875份血清样品中的HDCV抗体。所有样品均取自暴露于狂犬病前3次或暴露后5次接受HDCV全程预防接种者。以美国疾病控制中心(CDC)目前认定的RFFIT滴度1:5为有效水平。按照接种途径(肌肉1.0ml或皮内0.1ml)、性别及是否PCV分为8个试验组。对每组作Kaplan-Meier残量曲线,并用Wilcoxan X~2试验作各组的比较。
The authors tested HDCV antibodies in 875 serum samples from Americans and from Peace Corps Volunteers (PCV) using the Rapid Focal Inhibition Assay (RFFIT). All samples were taken from subjects exposed to rabies for 3 times or exposed to HDCV 5 times. To the United States Centers for Disease Control (CDC) currently identified RFFIT titer of 1: 5 as a valid level. According to the route of administration (muscle 1.0ml or intradermal 0.1ml), sex and whether PCV is divided into eight experimental groups. Kaplan-Meier residual curves were plotted for each group and compared using the Wilcoxan X ~ 2 test for each group.