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目的:观察葛根素注射液联合西药治疗少动和强直型帕金森病的临床疗效。方法:采用前瞻性的随机对照试验,将60例患者随机分为试验组30例,对照组30例。观察2组患者治疗前后进步率、生活质量的变化。结果:2组进步率疗效比较,差异有显著性意义(P<0.05)。试验组治疗后生活质量评分均有明显改善,与治疗前比较,差异有显著性或非常显著性意义(P<0.05,P<0.01);2组治疗后比较,差异有显著性意义(P<0.05)。表明在生活质量改善方面,试验组效果明显优于对照组。结论:葛根素注射液对改善少动和强直型帕金森病患者的生活质量有明显的疗效。
Objective: To observe the clinical effect of puerarin injection combined with Western medicine in the treatment of atopic and tetanic Parkinson’s disease. Methods: A prospective randomized controlled trial, 60 patients were randomly divided into experimental group 30 cases, control group 30 cases. The changes of the progress rate and quality of life before and after treatment in two groups were observed. Results: There was significant difference between two groups (P <0.05). The quality of life of the experimental group after treatment were significantly improved, compared with before treatment, the difference was significant or very significant (P <0.05, P <0.01); two groups after treatment, the difference was statistically significant (P < 0.05). Show that in improving the quality of life, the experimental group was significantly better than the control group. CONCLUSION: Puerarin injection has a significant effect on improving the quality of life of patients with atypical and tonic Parkinson’s disease.