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头孢氨苄(cephalexin)又称先锋Ⅳ,主要用于耐青霉素的葡萄球菌、链球菌、肺炎球菌、大肠杆菌等的感染。目前,测定方法有分光光度法、光化学荧光法、动力学催化法等。Nightingle等报道以0.10mol/L NaOH为介质,进行荧光分析快速、方便且灵敏。本文研究了头孢氨苄在酸性介质中的降解反应,应用于实际样品中测定,结果满意。
Cephalexin (cephalexin), also known as Pioneer IV, is mainly used for penicillin-resistant staphylococcus, streptococcus, pneumococcus, E. coli infection. At present, the determination of spectrophotometry, photochemical fluorescence, kinetic catalysis and so on. Nightingle et al reported 0.10mol / L NaOH as a medium for fluorescence analysis fast, convenient and sensitive. In this paper, the degradation of cephalexin in acidic medium was studied and applied to the determination of the actual samples, with satisfactory results.