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目的:将计算机引入小鼠游泳测试仪,为抗疲劳中药提供一套客观、准确的指标评价体系。方法:选用已完善的小鼠游泳计算机自动控制系统,对经典的抗疲劳中药人参进行动物实验,以建立抗疲劳指标评价体系。结果:小鼠游泳计算机自动控制系统所获数据游泳时间、不动时间、死亡时间、首次下沉时间、下沉时间、游泳距离、游泳时间比率、不动时间比率能准确、有效的评价反映小鼠的行为学改变,对抗疲劳中药的评价有意义。结论:基于小鼠游泳的计算机自动管理系统指标评价体系可用于抗疲劳中药的研究。
OBJECTIVE: To introduce a computer into a mouse swimming tester to provide an objective and accurate indicator evaluation system for anti-fatigue medicine. Methods: A computerized automatic control system for mouse swimming was selected to conduct an animal experiment on classical anti-fatigue Chinese ginseng to establish an evaluation system of anti-fatigue index. Results: The swimming time, dead time, first sunk time, sunk time, swimming distance, swimming time ratio and immobility time rate of mouse swimming computer automatic control system can accurately and effectively reflect small Changes in the behavior of rats, anti-fatigue evaluation of Chinese medicine makes sense. Conclusion: The evaluation index system based on mouse swimming automatic computer management system can be used for anti-fatigue Chinese medicine research.