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为了明确原发性甲状旁腺机能亢进症症状与治疗的新趋势,作者将新奥尔良慈善医院1970年以前治疗的100例(前组)跟1975年以来治疗的66例(后组)进行对比.后组病人的高发病率在61～70岁.而前组为51～60岁.两组中年轻病人的分布相同,因此,虽然近年来自动生化筛选方法的广泛应用,年轻病人中的早期诊断并未提高.前组病人中肾病发病率58%,后组中23%,估计是由于多导程分析仪和甲状旁腺素测定法使诊断更为有效,防止了继发于高血钙症的肾功能进一步恶化.后组病人中高血压的发病率四倍于前组.17个高血压病人在切除甲状旁腺后并未治愈,仅四例在手术后抗高血压药的剂量减少,根据这一分析,作者认为高血压病与甲状旁腺机能亢进症的关系可能有两种解释,第一,由于甲状旁腺机能亢进症在老年组中更为常见,因此高血压病较多是可以预计的,也就是说两者的关系仅是巧合.第二,高血钙引起的长期高血压使血管发生不可逆性改变,
To clarify the new trends in symptoms and treatment of primary hypoparathyroidism, the authors compared 100 patients treated in New Orleans Charity Hospital before 1970 (group before) to 66 patients treated since 1975 (group afterwards). The high incidence of patients in the latter group was between 61 and 70 years, while the former group was 51 to 60 years old.The distribution of young and middle-aged patients in both groups was the same, and therefore although early biochemical screening methods were widely used in recent years, early diagnosis in young patients Did not improve.The incidence of nephropathy in the former group of patients 58%, 23% in the latter group, it is estimated that the multi-lead analyzer and parathyroid hormone assay to make the diagnosis more effective to prevent secondary to hypercalcemia Of the renal function worsened in the latter group of patients with four times the incidence of hypertension in the former group.17 hypertensive patients after resection of the parathyroid did not heal, only four cases of postoperative antihypertensive dose reduced, according to This analysis, the author believes that hyperthyroidism and hyperparathyroidism may have two kinds of explanation of the relationship between the first, as hyperparathyroidism is more common in the elderly group, so more hypertension can be Expected, that is the relationship between the two is only Together. Second, long-term high blood pressure in the blood vessels caused by high blood calcium irreversible changes occur,