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目的分析该院2014年住院部抗菌药物应用情况与常见分离细菌耐药趋势。方法利用Excel对住院部2014年抗菌药物使用量、药敏试验数据进行统计、分析。结果头孢菌素类、青霉素类、β-内酰胺酶抑制药、氟喹诺类和大环内酯类是我院使用的主要品种,多种细菌已对常用抗菌药物产生较高耐药率。结论抗菌药物的用药频度(DDDS)与细菌耐药呈正相关关系,合理应用抗菌药物对提高疗效和减缓耐药有着重要意义。
Objective To analyze the application of antibacterials in hospital in 2014 and the trend of common bacterial isolates. Methods The data of antibiotic use and susceptibility test data of inpatient department in 2014 were statistically analyzed with Excel. Results Cephalosporins, penicillins, β-lactamase inhibitors, fluoroquinolones and macrolides were the main varieties used in our hospital. A variety of bacteria had high resistance rates to common antibacterials. Conclusion The frequency of antimicrobial medication (DDDS) is positively correlated with bacterial resistance, and rational use of antimicrobial agents is of great importance to improve the curative effect and reduce the drug resistance.