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本文作者试图弄清那些对声门下疤痕形成可能有病源学意义的因素,以期借此有助于预防和治疗。氏等假设由长期插管所致的喉气管损伤产生的伤口,若无感染并保持清洁则较可能顺利愈合而无疤;气管切开由于可引进明显的细菌污染而影响正在愈合的伤口稳定性,故可产生大量的疤痕。作者们根据定量的细菌学的概念,即感染的发生必须有一个细菌的临界组织水平,用下述定量的细菌学方法对以上假设进行验证。在12只成年狗中,通过内腔镜剥去左侧声门下粘膜,但不扰动其下面的肌肉或软骨,使在声带游离缘下造成1×2cm创面。其后将动物分为两组,各观察二周。组一不作气管切开,组二则同时在8—10气管环处做低位气管切开。在喉部
The authors sought to identify those factors that may have etiological significance for the formation of supraglottic scarring in order to help prevent and treat them. Et al. Hypothesized that wounds created by long-term intubation of the laryngotracheal tube wounds were more likely to heal without scarring if infected and kept clean; tracheotomy would affect the stability of the healing wound due to the introduction of significant bacterial contamination , It can produce a lot of scars. Based on the rationale of quantitative bacteriology, which states that infection must occur at the critical tissue level of bacteria, the authors validate the above hypothesis using the quantitative bacteriological method described below. In 12 adult dogs, the left subglottic mucosa was stripped by endoscope without disturbing the muscles or cartilage underlying it causing a 1 x 2 cm wound at the free edge of the vocal cords. The animals were then divided into two groups, each observed for two weeks. Group one without tracheostomy, group two at the same time in the 8-10 tracheal ring at the low tracheotomy. In the throat