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将血浆中[HCO3-]作为自变量、△PaCO2/△[HCO3-]作为因变量,对酸碱平衡紊乱中肺的缓冲作用进行了量化处理并初步建立了数学模型.利用两者间的函数关系,看到:代谢性酸中毒时,随着血浆中[HCO3-]值越来越小,△PaCO2/△[HCO3-]的变化率也越来越小;代谢性碱中毒时,随着血浆中[HCO3-]值越来越大,△PaCO2/△[HCO3-]的变化率越来越小.这一结果完全符合生物学规律.提示这一数学模型对研究酸碱平衡紊乱时,肺代偿调节机制、代偿强度等情况有一定的意义.
The plasma [HCO3-] as an independent variable, △ PaCO2 / △ [HCO3-] as a dependent variable in the acid-base balance disorders in the lung buffer were quantified and the initial establishment of a mathematical model using the function between the two Relationship, see: metabolic acidosis, with the plasma [HCO3-] value is getting smaller, △ PaCO2 / △ [HCO3-] rate of change is getting smaller and smaller; metabolic alkalosis, with the The value of [HCO3-] in plasma is getting bigger and bigger, and the rate of change of △ PaCO2 / △ [HCO3-] is getting smaller and smaller, which is in full accordance with the biological laws.It is suggested that when this mathematical model is used to study the acid- Lung compensatory adjustment mechanism, compensatory intensity and so on have some significance.