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[目的]探讨临床颈淋巴结阴性(CN0)的甲状腺乳头状癌中央区淋巴结清扫的临床意义。[方法]对2010年1月至2011年6月收治的178例CN0甲状腺乳头状癌患者行中央区淋巴结清扫,其中67例同期行外侧区淋巴结清扫。评估中央区淋巴结清扫术的安全性,并对中央区及外侧区淋巴结转移相关因素进行分析。[结果]中央区淋巴结清扫没有明显增加手术并发症。中央区淋巴结转移率为44.4%;中央区淋巴结转移率与肿瘤大小有关,外侧区淋巴结转移率与中央区淋巴结阳性数目有关。[结论]中央区淋巴结清扫是一个方便安全的手术,能使部分患者免除外侧区颈清扫,应列为CN甲状腺乳头状癌患者的常规选择。
[Objective] To investigate the clinical significance of lymph node dissection in central lymph node of papillary thyroid carcinoma with clinical cervical lymph node negative (CN0). [Method] A total of 178 patients with CN0 thyroid papillary carcinoma who were treated from January 2010 to June 2011 underwent lymphadenectomy in the central area, of which 67 cases were treated with lateral lymphadenectomy. To evaluate the safety of lymph node dissection in central area and to analyze the related factors of lymph node metastasis in central area and lateral area. [Results] The central lymph node dissection did not significantly increase the surgical complications. The central lymph node metastasis rate was 44.4%. The central lymph node metastasis rate was related to tumor size. The lateral lymph node metastasis rate was related to the positive lymph node number in the central area. [Conclusion] Lymph node dissection in the central area is a convenient and safe operation, which can relieve some patients from lateral neck dissection and should be a routine choice of patients with CN thyroid papillary carcinoma.