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本文采用随机双盲方法研究了局部滴用噻吗心安眼药水对运动状态下健康人体心血管的影响。其方法是：每个受试者一只眼运动前滴用０．５％噻吗心安或者０．９％生理盐水，在运动前和运动后１０分钟内测量受试者的心率和血压。结果表明应用噻吗心安者，运动后２、４、６、８分钟的心率明显低于对照组（Ｐ＜０，０５）；心率和动脉收缩压的乘积也明显降低，与对照组相比差别有显著性（Ｐ＜０．０５）。本次研究未发现局部应用０．５％噻吗心安对健康人体的血压产生显著的影响。
In this paper, a randomized double-blind method was used to study the effect of topical drops of timolol eye drops on healthy human cardiovascular system. The method was as follows: Before each exercise, 0.5% timolol or 0.9% physiological saline was used in one eye to measure the heart rate and blood pressure of the subject before exercise and within 10 minutes after exercise. The results showed that the application of timolol, 2, 4, 6 and 8 minutes after exercise, the heart rate was significantly lower than the control group (P <0,05); heart rate and arterial systolic blood pressure product was also significantly reduced compared with the control group There was significant (P <0.05). This study found no topical application of 0.5% timolol on blood pressure in healthy people have a significant impact.