一百年前就有经呼吸道接触所致的工业镉中毒的报导。吸入高浓度镉烟或粉尘时,经1至数小时有鼻及咽喉刺激感、头痛、头晕,以后出现恶心、呕吐、腹泻、发烧,24～36小时后有胸痛和呼吸困难。重症时出现肺水肿,继而引起心肺机能障碍,可在4～48小时后死亡。人的吸入致死浓度约为2,600～2,900mg/m~·3分。急性时一般看不到肾机能异常。低浓度长期接触的靶器官为肺和肾脏。肺脏出现肺气肿,肾脏则出现以低分子蛋白尿和 A hundred years ago, there were reports of industrial cadmium poisoning caused by respiratory tract contact. Inhalation of high concentrations of cadmium smoke or dust, the nose and throat irritation, headache, dizziness after 1 to several hours later nausea, vomiting, diarrhea, fever, chest pain and breathing difficulties after 24 to 36 hours. Severe pulmonary edema, which can cause heart and lung dysfunction, can be 4 to 48 hours after the death. Inhalation lethal concentration of about 2,600 ~ 2,900mg / m ~ · 3 points. Acute renal dysfunction generally do not see. Long-term exposure to low concentrations of target organs for the lungs and kidneys. Pulmonary emphysema appears, the kidneys appear low molecular proteinuria and