患者女姓,26岁,于1964年10月19日因咽痛、咽下困难、全身出现红色皮疹三天入院。患者于一年前患银屑病,经治疗无效,入院前六天开始自服氨基蝶呤,每日三次每次0.5毫克,服药前未查血象。服药初期未见不适,于第三天感到咽痛、咽下困难,口腔粘膜破溃和出血,扁桃体肿大,并伴有四肢发痒、寒战、发烧(37.9℃)、剧烈头痛,全身皮肤出现红色丘疹、浮肿和脱发等症状。曾在五官科诊断为咽炎,给予青霉素、土 Female patient name, 26 years old, on October 19, 1964 due to sore throat, swallowing difficulties, systemic red rash three days admitted. Patients with psoriasis a year ago, after treatment ineffective, starting six days before admission, taking aminopterin, 0.5 mg three times daily, before taking medication did not check the blood. No discomfort in the early stages of medication, sore throat, difficulty swallowing, mucosal ulceration and bleeding in the mouth, enlarged tonsils, and itchy, chills, fever (37.9 ° C), severe headache, Red papules, edema and hair loss and other symptoms. Encephalopathy was diagnosed as ENT, given penicillin, soil