突触体素（synaptophysin）是突触小泡膜上的一种含糖的膜结构蛋白。1985年，Jahn等[1]首先在大鼠脑中发现，因为它的分子量是38kD，所以Jahn等称之为P38。同年，德国肿瘤研究中心的Wieden－mann等o］在牛脑中也发现并且提纯了这种蛋白，把它命名为spoptophysin，周国民等［’? Synaptophysin is a sugar-containing membrane-structure protein on the synaptic vesicle membrane. In 1985, Jahn et al [1] were first found in the rat brain, and because of its molecular weight of 38 kD, Jahn et al. Called P38. In the same year, Wieden-Mann et al, the German Cancer Research Center, also found and purified this protein in bovine brain, named it spoptophysin,