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目的探讨分析常规脑脊液细胞学检查在病毒性脑炎诊断的应用价值。方法从2015年2月-2016年2月期间收治的病毒性脑炎患者中,选取80例作为研究对象,分别接受常规脑脊液细胞学检查和生化检查,将前者检查结果作为观察组,后者检查结果作为对照组。结果观察组检出细胞异常76例,检出率为95.00%,其中单纯小淋巴细胞比例上升41例、激活淋巴细胞14例、淋巴细胞比例上升17例、以淋巴细胞为主的混合细胞4例;对照组检出细胞异常62例,检出率为77.50%,其中单纯小淋巴细胞比例上升35例,激活淋巴细胞13例,淋巴细胞比例上升12例,以淋巴细胞为主的混合细胞2例。两种方法细胞异常检出率比较,差异存在统计学意义(P<0.05)。结论针对病毒性脑炎患者的临床诊断,常规脑脊液细胞学检查具有稳定、敏感、直观、准确等特点,具有重要的诊断价值。
Objective To investigate the value of routine cerebrospinal fluid cytological examination in the diagnosis of viral encephalitis. Methods Eighty patients with viral encephalitis who were admitted during the period from February 2015 to February 2016 were enrolled in this study. They were subjected to routine cerebrospinal fluid cytology and biochemical tests respectively. The former was used as the observation group and the latter was examined Results as a control group. Results In the observation group, 76 cases of abnormal cell were detected, the detection rate was 95.00%. Among them, the proportion of simple small lymphocytes increased in 41 cases, the number of activated lymphocytes in 14 cases, the proportion of lymphocytes increased in 17 cases, the mixed lymphocyte predominance in 4 cases ; The control group detected 62 cases of abnormal cells, the detection rate was 77.50%, in which the proportion of simple small lymphocytes increased 35 cases, 13 cases of activated lymphocytes, lymphocytes increased in 12 cases, mainly mixed lymphocytes in 2 cases . There was a statistically significant difference between the two methods in the detection rate of cell abnormalities (P <0.05). Conclusion Clinical diagnosis of patients with viral encephalitis, conventional cerebrospinal fluid cytology is stable, sensitive, intuitive and accurate, has important diagnostic value.