论文部分内容阅读
目的:总结8例尸体肾移植术后严重巨细胞病毒(CMV)感染的治疗经验。方法:通过检测CMV┐IgM或(和)检测血中CMV┐DNA(PCR法),结合临床症状及胸片确立诊断。以丙氧鸟苷治疗,配合静脉滴注大剂量丙种球蛋白,适当减少免疫抑制剂,治疗/预防二重感染,加强营养等综合治疗。结果:治愈6例,死亡2例。结论:严重CMV感染致死率高,丙氧鸟苷加综合治疗措施的疗效是比较成功的
Objective: To summarize the experience of treatment of severe cytomegalovirus (CMV) infection in 8 patients after cadaveric kidney transplantation. Methods: The diagnosis of CMV ┐ IgM or (and) detection of CMV ┐ DNA in blood (PCR) combined with clinical symptoms and chest radiograph. With ganciclovir treatment, with high-dose intravenous infusion of gamma globulin, immunosuppressive agents appropriate to reduce the treatment / prevention of double infection, to enhance nutrition and other comprehensive treatment. Results: 6 cases were cured and 2 died. Conclusions: The mortality of severe CMV infection is high, and the efficacy of ganciclovir combined with comprehensive treatment is more successful