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目的研究无创正压通气对慢性阻塞性肺病(COPD)肺功能康复的作用。方法治疗组56例患者在常规治疗的基础上采用BiPAP呼吸机,经用鼻/面罩无创正压通气(NIPPV)治疗COPD、肺心病并Ⅱ型呼吸衰竭(呼衰),以同期住院达同样标准的患者32例仅采用常规治疗,加用呼吸兴奋剂治疗,作为对照组。结果两组治疗前后血气分析pH无明显变化(P>0.05),两组PaCO2均有降低,而治疗组有明显下降(P<0.01),两组PaO2及SaO2均有升高,而治疗组有明显升高(P<0.01)。结论BiPAP呼吸机进行无创NIPPV对COPD、肺心病并Ⅱ型呼衰的疗效较为肯定,可降低PaO提高PaO、减轻症状,有助于COPD患者的肺功能康复。
Objective To investigate the effect of noninvasive positive pressure ventilation on pulmonary function recovery in patients with chronic obstructive pulmonary disease (COPD). Methods Fifty-six patients in the treatment group were treated with BiPAP ventilator on the basis of conventional therapy. COPD, pulmonary heart disease and type Ⅱ respiratory failure (respiratory failure) were treated by nasal / mask non-invasive positive pressure ventilation (NIPPV) Of 32 patients with conventional therapy only, plus respiratory stimulant therapy, as a control group. Results Before and after treatment, blood pH did not change significantly (P> 0.05), PaCO2 in both groups decreased, but decreased significantly in the treatment group (P <0.01), PaO2 and SaO2 in both groups increased, while in the treatment group Was significantly higher (P <0.01). Conclusion BiPAP ventilator for non-invasive NIPPV on COPD, pulmonary heart disease and type Ⅱ respiratory failure more positive effect, can reduce PaO increase PaO, reduce symptoms, contribute to lung function in patients with COPD rehabilitation.