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目的探讨羊膜移植术在重建眼表面、治疗重度角结膜碱烧伤后遗血管性角膜白斑的作用。方法采用甘油保存的人羊膜移植术治疗兔重度角结膜碱烧伤后遗血管性角膜白斑１０例（１０眼）。结果４例羊膜上皮面朝上者，术后１５～２０ｄ角膜表面上皮被覆完整，３０ｄ病理显示结膜上皮向角膜上皮转化；５例朝下和１例羊膜水肿者，术后羊膜被破坏，眼表面重建失败。结论羊膜移植术可用于重度角结膜碱烧伤晚期眼表面重建，支持羊膜无抗原性、有助于角膜上皮形成的观点
Objective To investigate the role of amniotic membrane transplantation in reconstructing ocular surface and treating vasculitic leukoplakia after severe alkali conjunctival alkali burn. Methods Ten patients (10 eyes) with vascular corneal leukoplakia treated by glycerin - preserved human amniotic membrane transplantation were treated with severe alkali and conjunctival alkali burn. Results Four cases of amniotic epithelium face up, the corneal surface epithelium was completely covered 15 days to 20 days after operation, and the conjunctival epithelium was transformed into corneal epithelium on the 30th day. Five cases were down and one case had amniotic membrane edema. Reconstruction failed. Conclusion Amniotic membrane transplantation can be used to reconstruct the late stage ocular surface of severe alkali conjunctival alkali burn and support the non-antigenicity of amniotic membrane and contribute to the formation of corneal epithelium