报道了扑热息痛（对乙酰氨基苯酚）的单扫描示波极谱法测定．扑热息痛的水解产物对氨基苯酚经重氮－偶氮化反应生成偶氮化合物，在ＮＨ３·Ｈ２Ｏ－ＮＨ４Ｃｌ底液中，该偶氮化合物在单扫描极谱上，峰电位－０．４０Ｖ（ｖｓ，ＳＣＥ）处产生灵敏的极谱波．扑热息痛在１×１０－７～５×１０－５ｍｏｌ／Ｌ浓度范围内与导数峰高成线性关系，检测限为５×１０－８／ｍｏｌ·Ｌ．探讨了极谱波的性质和电极反应机理．利用该方法测定了扑热息痛片剂和速效伤风胶囊中扑热息痛的含量，与分光光度法对照，结果良好． Reported the single-sweep oscillopolarographic determination of paracetamol (paracetamol). Acetaminophen, a hydrolyzate of paracetamol, was converted to azo compounds via diazo-azo reaction. The peak potential of the azo compound was -0.40V (vs, SCE) produce sensitive polarographic wave. Paracetamol in the concentration range of 1 × 10-7 ~ 5 × 10-5mol / L and the derivative peak height linear relationship with a detection limit of 5 × 10-8 / mol · L. The polarographic wave properties and electrode reaction mechanism were discussed. The paracetamol tablets and instant paraquat capsules were used to determine the content of paracetamol. Compared with spectrophotometry, the results were good.