SSLG was orally administered to rats dailyfor 6 successive days at a dosage of 100 mg/kgor 200 mg/kg body weight.Swimming experi-ment was then performed,and showed that theswimming time of the SSLG-treated rats wasmuch longer than that of a control group.Further,SSLG significantly raised the level ofblood lipid in rats both at rest and during swim-ming exercise and inhibited the increase ofblood lactic acid as well as the reduction ofthe liver and rectus femoris muscle(RFM)gly-cogens.SSLG also enhanced the amount ofprotein in the liver and RFM in rats at restand during swimming,and the content of RNAin the tissues at rest.However,for swimmingrats of both dosage groups the amounts of RNAand DNA in the liver and RFM show no signi-ficant difference.In vivo,SSLG showed noeffect on the respiratory quotient(RQ)of RFMof rats at rest,though the RQ of SSLG-treatedrats was lowered after 2 hrs of swimming.Invitro,the drug had no effect on RQ.The ex-periments showed the ability of saponins tofacilitate the release of fatty acid from epidi-dymal adipose tissue in rats.It was inferredthat the raising of blood lipid level by SSLGcould be one linkage in its anti-fatigue mechan-ism. SSLG was orally administered to rats daily for 6 successive days at a dosage of 100 mg / kg g 200 mg / kg body weight. Simming experiment-was performed, and showed that the soimming time of the SSLG-treated rats was longer than that of a control group. Future, SSLG significantly raised the level of blood lipid in rats both at rest and during swim-ming exercise and inhibited the increase of blood lactic acid as well as the reduction of the liver and rectus femoris muscle (RFM) gly-cogens. SLG also enhanced the amount ofprotein in the liver and RFM in rats at rest and during swimming, and the content of RNAin the tissues at rest. Host, for swimmingrats of both dosage groups the amounts of RNA and DNA in the liver and RFM show no signi-ficant difference . In vivo, SSLG showed no effect on the respiratory quotient (RQ) of RFMof rats at rest, though the RQ of SSLG-treatedrats was after after 2 hrs of swimming. Invitro, the drug had no effect on RQ. The ex-periments showed the ability of saponins tofacil itate the release of fatty acid from epidi-dymal adipose tissue in rats. It was inferred that the raising of blood lipid level by SSLGcould be one linkage in its anti-fatigue mechan-ism.