Purpose.To report the therapeutic o utcome of transpupil-lary thermotherapy(TTT)for subfoveal choroidal neovas-cularization(CNV)in brown retina using a diode-laser with the setting of lower energy level com pared to the previous studies on light-pigmented Caucasian patients.Methods.A total of 19subfoveal CNVs in 18patie nts were treated with TTT.The power of diode-laser was set160mWfor 1.2mm beam,270mW for 2.0mm beam,and 400mW for 3.0mm beam,and the laser was delivered f or 1min through a slit-lamp mounted delivery system.Patients were followed up for a mean of 8.8months(4-12months).Visual acuity and the fundus change as judged by funduscopic examination and simultaneous fluorescein and indocyanine green angiography were evaluated.Visual acuity was mea-sured by a Japanese standard Landolt visual acuity chart and converted to logarithm of the min imal angle resolution(logMAR)visual acuity for statistical analy sis .Improve-ment or decline in vision was defined as change of more than 0.2in log MAR visual acuity.Results.In eyes with minimally classic or occult only CNV,visual acuity im-proved in two eyes(18%)stabilized in seven eyes(64%)and worsened in two eyes(18%).In eyes with predomi-nantly classic CNV,visual acuity im proved in two eyes(25%),stabilized in four eyes(50%)and worsened in two eyes(25%).In all,15(84%)eyes of all studied subjects had improvement in exudati on.Two (11%)and one(5%)eye(s)were noted to have a significant post-treatment haemorrhage and retinal pigment epithelial tear,respectively.Conclusion.In patients with brown retinal colour,the treatment outco me of TTT was compa-rable to that of light-pigmented Cau casian patients with approximately half the laser power e nergy.Further ran-domized control studies are warrant ed. Purpose.To report the therapeutic o utcome of transpupil-lary thermotherapy (TTT) for subfoveal choroidal neovas-cularization (CNV) in brown retina using a diode-laser with the setting of lower energy level com pared to the previous studies on light-pigmented Caucasian patients. Methods total of 19 subfoveal CNVs in 18 patients were treated with TTT. The power of diode-laser was set 160 mm for 1.2 mm beam, 270 mW for 2.0 mm beam, and 400 mW for 3.0 mm beam, and the laser was delivered f or Patients were followed up for a mean of 8.8 months (4-12 months). Visual acuity and the fundus change as judged by funduscopic examination and simultaneous fluorescein and indocyanine green angiography were evaluated. Visual acuity was mea-sured by a Japanese standard Landolt visual acuity chart and converted to logarithm of the min imal angle resolution (logMAR) visual acuity for statistical analyze s. Improve-ment or decline in vision was defined as change of more than 0.2 in log MAR visual acuity. Results in eyes with minimally classic or occult only CNV, visual acuity im-proven in two eyes (18%) stabilized in seven eyes (64%) and worsened in two eyes (18%). with predomi-nantly classic CNV, visual acuity im proved in two eyes (25%), stabilized in four eyes (50%) and worsened in two eyes had improvement in exudati on. Tw (11%) and one (5%) eye (s) were noted to have a significant post-treatment haemorrhage and retinal pigment epithelial tear, respectively. Confluence in patients with brown retinal color, the treatment outco me of TTT was compa-rable to that of light-pigmented Cau casian patients with approximately half the laser power e nergy. Fuu ran-domized control studies are warrant ed.