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心钠素(Cardionatrin)是心房肌细胞所分泌的一种循环激素,具有强大利尿,利钠作用。最近报告,应用心钠素可以有效地治疗原发性高血压和心功能不全,对于原发性醛固酮增多症亦有一定的疗效。我们为一例酒精中毒性肝硬变腹水的患者试用心钠素,亦得到一定的效果,现简要报告如下。临床资料和方法临床资料患者男,39岁,因10多天来腹胀,腹部隆起,双下肢浮肿于1985年1月27日住院治疗。患者20多年来嗜酒,每日2～3两。5～6年来血压高,最高达140～150/100～110。50多天来无诱因腹泻,每天6～7次,便稀软,偶尔带血。既往无恶心、呕吐和肝炎史,无食物和药物中毒史。入院时体温37℃,心率80次,呼吸16次,血压130/80。
Cardionatrin (Cardionatrin) is a circulatory hormone secreted by atrial myocytes, with a strong diuretic, sodium role. Recently reported that the application of atrial natriuretic peptide can effectively treat essential hypertension and cardiac insufficiency, for primary aldosteronism also have a certain effect. We try atrial natriuretic peptide in patients with alcoholic cirrhosis ascites, also have some effect, are summarized as follows. Clinical data and methods Clinical data Patient Male, 39 years old, due to more than 10 days to bloating, abdominal bulge, lower extremity edema in January 27, 1985 hospitalization. 20 years of patients with alcohol, daily 2 to 3 two. 5 to 6 years high blood pressure, up to 140 ~ 150/100 ~ 110.50 more days to induce diarrhea, 6 to 7 times a day, then thin soft, and occasionally bloody. Past no nausea, vomiting and hepatitis history, no food and drug poisoning history. At admission, body temperature 37 ℃, heart rate 80 times, breathing 16 times, blood pressure 130/80.