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据报道,仲胺与亚硝酸(或亚硝酸盐)在动物或人体内外,于适当的酸度下,均能合成强烈的致癌物质——亚硝胺。合成亚硝胺的前体物如仲胺及其他胺类和亚硝酸盐等,广泛存在于食物中。据国内某些食管癌高发区的调查,发现醃制酸莱所含的亚硝胺及其前体均较高。现将我们对广东省鼻咽癌高发区的四会县(1970~1979年平均死亡率16.07/10万人口)、中山县(1970~1975年平均死亡率12.46/10万人口)及低发区五华县(1970~1972年平均死亡率1.67/10万)的调查结果报告如下。
It is reported that secondary amines and nitrite (or nitrite) in animals or humans, both within the appropriate acidity, can synthesize a strong carcinogen - nitrosamines. Precursors of synthetic nitrosamines such as secondary amines and other amines and nitrites are widely found in food. According to the survey of some high incidence of esophageal cancer in China, it is found that the nitrosamines and their precursors contained in the cured acidula are higher. Now we will analyze the prevalence rates of four county (average death rate of 16.07 / 100000 in 1970 ~ 1979), Zhongshan County (average mortality of 12.46 / 100000 in 1970 ~ 1975) and low incidence area Wuhua County (1970 to 1972, the average death rate of 1.67 / 100 000) the findings are as follows.