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本文报道了西澳大利亚巴塞尔镇人群中血清载脂蛋白A-Ⅰ和A-Ⅱ水平;影响A-Ⅰ和A-Ⅱ水平的因素;A-Ⅰ和A-Ⅱ水平与冠心病的关系。研究所得A-Ⅰ正常血清水平为1.48(±0.26)g/L;A-Ⅱ为相对值。A-Ⅰ水平女高于男,但仅在55岁以上各年龄组差异显著。饮酒、血清总胆固醇水平、女性体育锻炼者与A-Ⅰ和A-Ⅱ血清水平呈显著正相关,而女性甘油三酯水平仅与A-Ⅱ血清水平呈显著正相关。肥胖、男性甘油三酯水平与A-Ⅰ,女性肥胖、男性年龄与A-Ⅱ血清水平呈负相关。据Logistic回归分析,A-Ⅰ血清水平及男性A-Ⅱ血清水平与冠心病发病率呈显著负相关而年龄、男性甘油三酯水平与之呈显著正相关。
This paper reports the serum apolipoprotein A-I and A-II levels in the population of Basel in Western Australia; the factors that affect the level of A-I and A-II; the relationship between A-I and A-II levels and coronary heart disease. The normal serum level of A-Ⅰ was 1.48 (± 0.26) g / L and A-Ⅱ was relative. A-Ⅰ level higher than men, but only in 55 years of age significantly different groups. Alcohol consumption, serum total cholesterol, female physical exercisers had a significant positive correlation with serum levels of A-Ⅰ and A-Ⅱ, but women’s triglyceride level had only a significant positive correlation with A-Ⅱ serum level. Obesity, male triglyceride levels and A-Ⅰ, female obesity, male age and serum A-Ⅱ levels were inversely correlated. Logistic regression analysis showed that A-Ⅰ serum levels and male A-Ⅱ serum levels were significantly negatively correlated with the incidence of coronary heart disease, but age and male triglyceride levels were positively correlated with them.