论文部分内容阅读
目的探讨肝硬化伴肝癌肝移植前等待期经过肿瘤灭活对其移植术后生存率的影响。方法对19例肝硬化伴肝癌病人14例术前用动脉化疗栓塞(TACE)或射频消融(RFA)进行肿瘤灭活并与同组5同期未行肿瘤灭活者比较其对术后肿瘤复发及生存率的影响。结果本组19例,随访6~61月,18例获无瘤存活,其中术前行RFA的4例病理见肿瘤坏死;10例TACE中有9例肿瘤有坏死,已平均存活18.1月。未行治疗的6例中1例于术后4个月骨转移,带瘤存活12个月后死亡。结论肝硬化伴肝癌在移植术前等待期用TACE或射频消融行肿瘤灭活,对提高肝癌肝移植远期疗效、提高术后生存率有显著意义。
Objective To investigate the influence of tumor inactivation on the survival rate of patients with liver cirrhosis and liver cancer before transplantation after waiting period. Methods Twenty-nine patients with cirrhosis and hepatocellular carcinoma (HCC) were treated with TACE or radiofrequency ablation (RFA) before surgery and compared with those without tumor inactivation during the same period. The impact of survival. Results Twenty-nine patients were followed up for 6 to 61 months. Twenty-eight patients survived without tumor. Among them, 4 patients with RFA showed tumor necrosis before operation; 9 of 10 TACE patients had necrosis and had an average survival of 18.1 months. One of the 6 patients who did not receive treatment had bone metastases 4 months after the operation and died after 12 months of survival. Conclusions The treatment of liver cirrhosis with hepatocellular carcinoma by TACE or radiofrequency catheter ablation during the waiting period before transplantation is of great significance to improve the long-term efficacy of liver transplantation and improve the postoperative survival rate.