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目的:针对临床上采用氯吡格雷联合阿司匹林治疗急性心肌梗死的效果及安全性进行分析。方法:将2016年1月至2017年1月因急性心肌梗死到我院接受治疗的64例患者随机分为治疗组和对照组。对照组32例患者采用阿司匹林药物治疗,治疗组32例患者将阿司匹林与氯吡格雷这种药物联合起来予以治疗,对这两组患者治疗效果进行比较。结果:治疗组患者的心脏血管复通率、再闭塞率分别为43.75%、3.13%,明显低于对照组的46.88%、6.25%;治疗组左心室射血分数明显高于对照组、血小板聚集率明显低于对照组(P<0.05)。结论:临床上针对急性心肌梗死的治疗,在阿司匹林的基础上加施氯吡格雷的效果更为显著,能在治疗阶段有效改善患者的心功能,防止血小板聚集,方法值得借鉴。
Objective: To analyze the clinical effect and safety of clopidogrel combined with aspirin in the treatment of acute myocardial infarction. Methods: 64 patients with acute myocardial infarction who were treated in our hospital from January 2016 to January 2017 were randomly divided into treatment group and control group. 32 patients in the control group were treated with aspirin, 32 patients in the treatment group were treated with aspirin and clopidogrel, and the treatment effect was compared between the two groups. Results: The rate of recanalization and reocclusion of heart vessel in treatment group were 43.75% and 3.13% respectively, which was significantly lower than 46.88% and 6.25% in control group. The left ventricular ejection fraction in treatment group was significantly higher than that in control group and platelet aggregation The rate was significantly lower than that of the control group (P <0.05). Conclusion: The clinical treatment of acute myocardial infarction, aspirin plus clopidogrel on the basis of the more significant effect, can effectively improve the patient’s cardiac function in the treatment phase, to prevent platelet aggregation, the method is worth learning.