对钩虫低感染人群目标化疗效果进行了初步观察,结果对钩虫感染率较高的年龄组(>41岁)进行一次目标化疗一年后下降率42.16%,这与以前感染程度最高的村集体化疗一年后的下降率45.33%相当。因此,在肠线虫病防治后期,可以有针对性地结合当地肠线虫病流行特点,采取不同的目标化疗措施,可以合理使用药物和发挥更大的驱虫效果,减少实施过程中的工作量和药物耗量以及延缓药物抗性的产生,起到事半功倍的作用。 A preliminary observation on the effect of targeted chemotherapy in low infection rate of hookworm showed that the rate of decline after one year of target chemotherapy was 42.16% in the group with higher infection rate of hookworm (> 41 years old), which was the same as that of the village collective chemotherapy After a year the rate of decline of 45.33%. Therefore, in the late stage of prevention and treatment of intestinal nematode disease, it can be targeted with the local characteristics of intestinal nematode disease, take different target chemotherapy, rational use of drugs and play a greater deworming effect, reduce the workload of the implementation process and Drug consumption and delay the emergence of drug resistance, play a multiplier effect.