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目的:考察复方磺胺甲唑片释放度。方法:参照美国药典(ⅩⅫ),采用桨法和双波长分光光度法测定5种不同厂家批次的复方磺胺甲唑片释放度。结果:5种不同厂家批次的复方磺胺甲唑片释放度有非常显著差异(P<001)。结论:有必要增加释放度检查以保证国产复方磺胺甲:目的:考察复方磺胺甲唑片释放度。方法:参照美国药典(ⅩⅫ),采用桨法和双波长分光光度法测定5种不同厂家批次的复方磺胺甲唑片释放度。结果:5种不同厂家批次的复方磺胺甲唑片释放度有非常显著差异(P<001)。结论:有必要增加释放度检查以保证国产复方磺胺甲唑质量。
Objective: To investigate the release of compound sulfamethoxazole tablets. Methods: According to the United States Pharmacopoeia (ⅩⅫ), the release of compound sulfamethoxazole tablets from 5 batches of different manufacturers was determined by paddle method and dual-wavelength spectrophotometry. Results: There were significant differences in the release of sulfamethoxazole tablets between five batches of different manufacturers (P <001). Conclusion: It is necessary to increase the release test to ensure that the domestic compound sulfamethoxazole: Aim: To investigate the release of sulfamethoxazole tablets. Methods: According to the United States Pharmacopoeia (ⅩⅫ), the release of compound sulfamethoxazole tablets from 5 batches of different manufacturers was determined by paddle method and dual-wavelength spectrophotometry. Results: There were significant differences in the release of sulfamethoxazole tablets between five batches of different manufacturers (P <001). Conclusion: It is necessary to increase the release test to ensure the quality of domestic compound sulfamethoxazole.