为了观察通脉益智胶囊对小鼠反复脑缺血再灌流后行为学的影响，我们将４０只小鼠分为４组，经反复脑缺血再灌加降血压法造模后，分别给予生理盐水、通脉益智胶囊、喜德镇灌胃，术后进行跳台、水迷宫实验测试。结果显示，模型组小鼠潜伏期缩短、游全程时间延长、错误次数增多；通脉益智胶囊组能使上述指标好转，统计学上有显著差异。本实验证实了反复脑缺血再灌流明显造成了小鼠学习、记忆功能障碍，而通脉益智胶囊可对抗此障碍，提高学习、记忆能力。 In order to observe the effect of Tongmai Yizhi Capsule on the behavior of mice after repeated cerebral ischemia and reperfusion, we divided 40 mice into 4 groups. After repeated cerebral ischemia and hypoperfusion, models were given after Normal saline, Tongmai puzzle capsules, Xidezhen gavage, post-surgery, water maze test. The results showed that the mice in the model group had shorter latency, longer travel time, and more errors. The Tongmai Yizhi Capsule group could improve the above indicators and had statistically significant differences. This experiment confirmed that repeated cerebral ischemia and reperfusion can cause learning and memory dysfunction in mice, and Tongmai Yizhi Capsule can combat this disorder and improve learning and memory ability.