论文部分内容阅读
骨髓增生异常综合征(MDS)是造血多能于细胞水平上的恶性变,所致分化障碍而引起的一种克隆病。其诊断主要依据周围血和骨髓涂片内的细胞形态学改变。血液表现为一系、二系或三系血细胞的减少,但各系间的减少程度可呈不均一性。髓象示增生活跃或极度活跃,伴网硬蛋白纤维增多,偶可因“血抽”而致假性增生低下,有二系或三系造血细胞的发育异常(病态造血)为主要特征。但是,除了原始(粒)细胞过多外,血细胞形态学所见一般无特异诊断价值.此外,临床上尚需注意排除有血细胞发育异常表现的其它疾患。
Myelodysplastic syndrome (MDS) is a Crohn’s disease caused by the differentiation disorder caused by the malignant transformation of hematopoietic cells at the cellular level. The diagnosis is mainly based on the changes of cell morphology in the peripheral blood and bone marrow smear. Blood showed a series, two or three lines of blood cells decreased, but the degree of reduction can be showed between the heterogeneity. Medulla shows that hyperkinetic activity or extreme hyperactivity, with increased network of protein fibers, even due to “blood pumping” and caused by hypoplasia low, with two or three lines of hematopoietic cells dysplasia (morbid hematopoietic) as the main feature. However, there is generally no specific diagnostic value for hemocyte morphology except for the excess of primitive (granulocytic) cells, and other disorders that preclude the display of abnormal blood cell development are clinically noted.