论文部分内容阅读
目的探讨肺癌患者伴深部真菌感染的危险因素、防治措施。方法回顾性分析我院36例肺癌患者发生肺深部真菌感染的诱因、临床表现、诊治等。结果肺癌患者肺深部真菌感染的病原菌以白色念珠菌为主,占69.4%(25/36)。肺癌的分期晚、患者年龄大、白细胞减少、滥用抗生素、侵入性诊疗等因素为真菌感染的危险因素。患者临床表现不典型,诊断以微生物培养为主。应用以氟康唑为主的综合治疗后,32例治愈,4例死亡。结论肺癌伴深部真菌感染有多种因素,应早期预防为主,确诊后及时应用氟康唑治疗有较好的疗效,同时应加强免疫与支持疗法。
Objective To investigate the risk factors and prevention and treatment of deep fungal infection in patients with lung cancer. Methods Retrospective analysis of 36 patients with lung cancer in our hospital induced lung deep fungal causes, clinical manifestations, diagnosis and treatment. Results Candida albicans was the main pathogen of lung deep fungal infection in lung cancer patients, accounting for 69.4% (25/36). Late stage of lung cancer, patients with older, leukopenia, abuse of antibiotics, invasive diagnosis and treatment and other factors for the risk factors for fungal infections. Patients with atypical clinical manifestations, the diagnosis of microbial culture-based. Application of fluconazole-based comprehensive treatment, 32 patients were cured, 4 patients died. Conclusions Lung cancer with deep fungal infection has many factors, should be the early prevention, timely diagnosis of fluconazole after treatment has a good effect, should strengthen the immune and supportive therapy.