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目的：研究乙肝后肝硬化患者消化性溃疡的临床特点，探讨小剂量心得安对肝源性溃疡愈合的影响。方法：肝源性溃疡４５例，观察其发病年龄、临床表现、溃疡部位、ＨＰ感染率、合并出血率及溃疡愈合率等特点。随机分为治疗组（Ａ组）２３例，用心得安＋泰胃美口服治疗；对照组（Ｂ组）２２例，用维生素Ｂ６＋泰胃美口服治疗。另外选单纯性消化性溃疡２２例，作为对照２组（Ｃ组），治疗方法与Ｂ组相同。结果：肝源性溃疡发病年龄较单纯性消化性溃疡晚１０年，溃疡部位以胃溃疡居多，合并出血率高，较对照Ｃ组有显著性差异（Ｐ＜０．０１）。心得安可明显提高肝源性溃疡愈合率，与对照Ｂ组具统计学意义（Ｐ＜０．０５）。结论：肝源性溃疡难以治愈且易合并出血，门静脉高压因素可能从中发挥作用，小剂量心得安有助于肝源性溃疡愈合。
Objective: To study the clinical characteristics of peptic ulcer in patients with posthepatitic cirrhosis and to explore the effect of low dose propranolol on the healing of hepatic ulcer. Methods: Forty-five patients with liver-derived ulcer were observed for their age, clinical manifestations, ulcer location, HP infection rate, combined hemorrhage rate and ulcer healing rate. Randomly divided into treatment group (A group) 23 cases, with propranolol + Tai Weimei oral treatment; control group (B group) 22 cases, with vitamin B6 + Thai Weimei oral treatment. Another menu pure peptic ulcer in 22 cases, as a control group 2 (C group), treatment and B group the same. Results: The incidence of liver-derived ulcer was 10 years later than that of simple peptic ulcer. The ulcer was mainly gastric ulcer with high bleeding rate, which was significantly different from that of control group C (P <0.01). Experience Encore significantly improve the healing rate of liver ulcer, and the control group B with statistical significance (P <0.05). Conclusion: Hepatic ulcer is difficult to cure and easy to hemorrhage. The portal hypertension factors may play a role in it. Small dose of propranolol helps to heal liver ulcer.