论文部分内容阅读
糖尿病的病因与遗传有关,而胰岛素依赖型糖尿病(简称 IDDM)不仅与遗传有关,主要还与病毒感染及自身免疫有关。在多数特别是新发病的IDDM 患者血清中,能测得胰岛细胞抗体(简称ICA),有力地支持胰岛 B 细胞选择性地受损是自身免疫反应所致。我院以新鲜 O 型人胰作抗原,以间接免疫荧光法测定了57例糖尿病患者的血清 ICA,报告如下。材料和方法一、一般资料:57例糖尿病患者中9例 IDDM,全部为男性,年龄23～41(平均33)岁;48例 NIDDM(非胰岛素依赖型糖尿病),男29例,女19例,年龄35～75(平均55.2)岁。二、ICA 测定:(一)抗原的制备:取死后1小时以内的 O 型
The etiology of diabetes and genetic, and insulin-dependent diabetes (IDDM) not only with the genetic, mainly with the virus infection and autoimmunity. In most, especially newly diagnosed IDDM patients, the ability to measure islet cell antibodies (ICA), strongly supporting the selective destruction of islet B cells, is due to an autoimmune response. Our hospital with fresh O-type human pancreas as antigen, indirect immunofluorescence assay of 57 cases of diabetes, serum ICA, the report is as follows. Materials and Methods First, the general information: 9 cases of IDDM in 57 patients with diabetes, all male, aged from 23 to 41 (average 33) years; 48 cases of NIDDM (non-insulin dependent diabetes mellitus), 29 males and 19 females, Age 35 ~ 75 (average 55.2) years old. Second, ICA determination: (A) Preparation of antigen: take less than 1 hour after the death of the O-type